Eosinophilic Reaction at the Time of Catheter Insertion Predicts Survival in Patients Initiating Peritoneal Dialysis.

ABSTRACT:

Introduction

Despite excellent biocompatibility, insertion of silicone peritoneal dialysis (PD) catheters can induce minor foreign body reaction, affecting long-term patient outcomes. We evaluated the effect of eosinophilic reaction associated with PD catheter insertion on outcomes of patients initiating PD.

Methods

Eosinophilic reaction to PD catheter insertion was defined as the ratio of peripheral blood eosinophil count at 1 week after insertion (E1W) to pre-insertion eosinophil count (E0), and the association of E1W/E0 with technique survival, peritonitis-free survival, and heart failure (HF)-related hospitalization-free survival was analyzed.

Results

This retrospective cohort study included 116 patients (89 male patients) who underwent PD catheter insertion betwe

SUBMITTER: Uchiyama K 

PROVIDER: S-EPMC9116602 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature