Investigation of functional near-infrared spectroscopy signal quality and development of the hemodynamic phase correlation signal.

ABSTRACT: Significance: There is a longstanding recommendation within the field of fNIRS to use oxygenated ( HbO2 ) and deoxygenated (HHb) hemoglobin when analyzing and interpreting results. Despite this, many fNIRS studies do focus on HbO2 only. Previous work has shown that HbO2 on its own is susceptible to systemic interference and results may mostly reflect that rather than functional activation. Studies using both HbO2 and HHb to draw their conclusions do so with varying methods and can lead to discrepancies between studies. The combination of HbO2 and HHb has been recommended as a method to utilize both signals in analysis. Aim: We present the development of the hemodynamic phase correlation (HPC) signal to combine HbO2 and HHb as recommended to utilize both signals in the analysi

SUBMITTER: Hakim U 

PROVIDER: S-EPMC9116886 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature