Prognostic Interplay Between COVID-19 and Heart Failure With Reduced Ejection Fraction.

ABSTRACT:

Background

COVID-19 may negatively impact the prognosis of patients with chronic HFrEF and vice versa.

Methods

This study included 2 parallel analyses of patients in the United States who were in the TriNetX health database and who underwent polymerase chain reaction testing for SARS-CoV-2 as an inpatient or outpatient between January and September of 2020. Analysis A included patients with positive tests for COVID-19 and compared patients with histories of worsening heart failure with reduced ejection fraction (HFrEF) (hospitalization due to heart failure (HF) or IV diuretic use during the prior 12 months), HFrEF without worsening, and no prior HF. Analysis B included patients with histories of HFrEF and compared patients with positive vs negative COVID-19 tests. Outcomes i

SUBMITTER: Greene SJ 

PROVIDER: S-EPMC9116978 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature