Remdesivir for the treatment of COVID-19: a systematic review and meta-analysis.

ABSTRACT:

Background

The benefits of remdesivir in the treatment of hospitalized patients with COVID-19 remain debated with the National Institutes of Health and the World Health Organization providing contradictory recommendations for and against use.

Objectives

To evaluate the role of remdesivir for hospitalized inpatients as a function of oxygen requirements.

Data sources

Beginning with our prior systematic review, we searched MEDLINE using PubMed from 15 January 2021 through 5 May 2022.

Study eligibility criteria

Randomised controlled trials; all languages.

Participants

All hospitalized adults with COVID-19.

Interventions

Remdesivir, in comparison to either placebo, or standard of care.

Assessment of risk of bias

We used the ROB-2 criteria.

Me

SUBMITTER: Lee TC 

PROVIDER: S-EPMC9117160 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature