Antimicrobial potential and osteoblastic cell growth on electrochemically modified titanium surfaces with nanotubes and selenium or silver incorporation.

ABSTRACT: Titanium nanotube surfaces containing silver, zinc, and copper have shown antimicrobial effects without decreasing osteoblastic cell growth. In this in-vitro study we present first results on the biological evaluation of surface modifications by incorporating selenium and silver compounds into titanium-dioxide (TiO₂) nanotubes by electrochemical deposition. TiO₂-nanotubes (TNT) and Phosphate-doped TNT (pTNT) were grown on the surface of Ti6Al4V discs by anodization. Hydroxyapatite (HA), selenium (Se) and silver (Ag) compounds were incorporated by electrochemical deposition. Colony forming units of Staphylococcus epidermidis (DSM 3269) were significantly decreased in SepTNT (0.97 ± 0.18 × 10⁶ CFU/mL), SepTNT-HA (1.2 ± 0.39 × 10⁶ CFU/mL), AgpTNT (1

SUBMITTER: Staats K 

PROVIDER: S-EPMC9117198 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature