A compilation of fecal microbiome shotgun metagenomics from hematopoietic cell transplantation patients.

ABSTRACT: Hospitalized patients receiving hematopoietic cell transplants provide a unique opportunity to study the human gut microbiome. We previously compiled a large-scale longitudinal dataset of fecal microbiota and associated metadata, but we had limited that analysis to taxonomic composition of bacteria from 16S rRNA gene sequencing. Here we augment those data with shotgun metagenomics. The compilation amounts to a nested subset of 395 samples compiled from different studies at Memorial Sloan Kettering. Shotgun metagenomics describes the microbiome at the functional level, particularly in antimicrobial resistances and virulence factors. We provide accession numbers that link each sample to the paired-end sequencing files deposited in a public repository, which can be directly accessed by the on

SUBMITTER: Yan J 

PROVIDER: S-EPMC9117330 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature