Association Between Neddylation and Immune Response.
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ABSTRACT:
SUBMITTER: Zhu J
PROVIDER: S-EPMC9117624 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Publications
Association Between Neddylation and Immune Response.
Zhu Jiali J Chu Feng F Zhang Meirong M Sun Wenhuan W Zhou Fangfang F
Frontiers in cell and developmental biology 20220505
Neddylation is a ubiquitin-like post-translational protein modification. It occurs <i>via</i> the activation of the neural precursor cell expressed, developmentally downregulated protein 8 (NEDD8) by three enzymes: activating enzyme, conjugating enzyme, and ligase. NEDD8 was first isolated from the mouse brain in 1992 and was initially considered important for the development and differentiation of the central nervous system. Previously, the downregulation of neddylation was associated with some ...[more]
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