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WAO-ARIA consensus on chronic cough - Part III: Management strategies in primary and cough-specialty care. Updates in COVID-19.


ABSTRACT:

Background

Chronic cough management necessitates a clear integrated care pathway approach. Primary care physicians initially encounter the majority of chronic cough patients, yet their role in proper management can prove challenging due to limited access to advanced diagnostic testing. A multidisciplinary approach involving otolaryngologists and chest physicians, allergists, and gastroenterologists, among others, is central to the optimal diagnosis and treatment of conditions which underly or worsen cough. These include infectious and inflammatory, upper and lower airway pathologies, or gastro-esophageal reflux. Despite the wide armamentarium of ancillary testing conducted in cough multidisciplinary care, such management can improve cough but seldom resolves it completely. This can be due partly to the limited data on the role of tests (eg, spirometry, exhaled nitric oxide), as well as classical pharmacotherapy conducted in multidisciplinary specialties for chronic cough. Other important factors include presence of multiple concomitant cough trigger mechanisms and the central neuronal complexity of chronic cough. Subsequent management conducted by cough specialists aims at control of cough refractory to prior interventions and includes cough-specific behavioral counseling and pharmacotherapy with neuromodulators, among others. Preliminary data on the role of neuromodulators in a proof-of-concept manner are encouraging but lack strong evidence on efficacy and safety.

Objectives

The World Allergy Organization (WAO)/Allergic Rhinitis and its Impact on Asthma (ARIA) Joint Committee on Chronic Cough reviewed the recent literature on management of chronic cough in primary, multidisciplinary, and cough-specialty care. Knowledge gaps in diagnostic testing, classical and neuromodulator pharmacotherapy, in addition to behavioral therapy of chronic cough were also analyzed.

Outcomes

This third part of the WAO/ARIA consensus on chronic cough suggests a management algorithm of chronic cough in an integrated care pathway approach. Insights into the inherent limitations of multidisciplinary cough diagnostic testing, efficacy and safety of currently available antitussive pharmacotherapy, or the recently recognized behavioral therapy, can significantly improve the standards of care in patients with chronic cough.

SUBMITTER: Rouadi PW 

PROVIDER: S-EPMC9117692 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature

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Publications

WAO-ARIA consensus on chronic cough - Part III: Management strategies in primary and cough-specialty care. <i>Updates in</i> <i>COVID-19</i>.

Rouadi Philip W PW   Idriss Samar A SA   Bousquet Jean J   Laidlaw Tanya M TM   Azar Cecilio R CR   Al-Ahmad Mona S MS   Yañez Anahi A   Al-Nesf Maryam Ali Y MAY   Nsouli Talal M TM   Bahna Sami L SL   Abou-Jaoude Eliane E   Zaitoun Fares H FH   Hadi Usamah M UM   Hellings Peter W PW   Scadding Glenis K GK   Smith Peter K PK   Morais-Almeida Mario M   Maximiliano Gómez René R   Gonzalez Diaz Sandra N SN   Klimek Ludger L   Juvelekian Georges S GS   Riachy Moussa A MA   Canonica Giorgio Walter GW   Peden David D   Wong Gary W K GWK   Sublett James J   Bernstein Jonathan A JA   Wang Lianglu L   Tanno Luciana K LK   Chikhladze Manana M   Levin Michael M   Chang Yoon-Seok YS   Martin Bryan L BL   Caraballo Luis L   Custovic Adnan A   Ortego-Martell Jose Antonio JA   Lesslar Olivia J Ly OJL   Jensen-Jarolim Erika E   Ebisawa Motohiro M   Fiocchi Alessandro A   Ansotegui Ignacio J IJ  

The World Allergy Organization journal 20220514 5


<h4>Background</h4>Chronic cough management necessitates a clear integrated care pathway approach. Primary care physicians initially encounter the majority of chronic cough patients, yet their role in proper management can prove challenging due to limited access to advanced diagnostic testing. A multidisciplinary approach involving otolaryngologists and chest physicians, allergists, and gastroenterologists, among others, is central to the optimal diagnosis and treatment of conditions which under  ...[more]

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