In Vivo Bioconcentration of 10 Anionic Surfactants in Rainbow Trout Explained by In Vitro Data on Partitioning and S9 Clearance.

ABSTRACT: Bioconcentration factors (BCFs) in rainbow trout were measured for 10 anionic surfactants with a range of alkyl chain lengths and different polar head groups. The BCFs ranged from 0.04 L kg^-1 ww (for C₁₀SO₃) to 1370 L kg^-1 ww (C₁₆SO₃). There was a strong correlation between the log BCF and log membrane lipid-water distribution ratio (D_MLW, r² = 0.96), and biotransformation was identified as the dominant elimination mechanism. The strong positive influence of D_MLW on BCF was attributed to two phenomena: (i) increased partitioning from water into the epithelial membrane of the gill, leading to more rapid diffusion across this barrier and more rapid uptake, and (ii) increase

SUBMITTER: Ribbenstedt A 

PROVIDER: S-EPMC9118553 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature