An updated database of human maximum skin fluxes and epidermal permeability coefficients for drugs, xenobiotics, and other solutes applied as aqueous solutions.

ABSTRACT: The dataset represented in this article is referred to by the review article entitled "Topical drug delivery: history, percutaneous absorption, and product development" (MS Roberts et al., 2021) [1]. The dataset contains maximal flux (J_max ), and permeability coefficient (k_p ) values collated from In Vitro human skin Permeation Test (IVPT) reports published to date for various drugs, xenobiotics, and other solutes applied to human epidermis from aqueous solutions. Also included are each solute's physicochemical properties and the experimental conditions, such as temperature, skin thickness, and skin integrity, under which the data was generated. This database is limited to diluted or saturated aqueous solutions of solutes applied on human epiderma

SUBMITTER: Cheruvu HS 

PROVIDER: S-EPMC9118613 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature