Search for morphological indicators that predict implantation by principal component analysis using images of blastocyst.

ABSTRACT:

Background

Although the current evaluation of human blastocysts is based on the Gardner criteria, there may be other notable parameters. The purpose of our study was to clarify whether the morphology of blastocysts has notable indicators other than the Gardner criteria.

Methods

To find such indicators, we compared blastocysts that showed elevated human chorionic gonadotropin (hCG) levels after transplantation (hCG-positive group; n = 129) and those that did not (hCG-negative group; n = 105) using principal component analysis of pixel brightness of the images.

Results

The comparison revealed that the hCG-positive group had grainy morphology and the hCG-negative group had non-grainy morphology. Classification of the blastocysts by this indicator did not ma

SUBMITTER: Mashiko D 

PROVIDER: S-EPMC9119295 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature