Dataset Information

Instant inactivation of aerosolized SARS-CoV-2 by dielectric filter discharge.

ABSTRACT: This study aimed to evaluate the instant inactivation effect of dielectric filter discharge (DFD) on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) aerosols. The filter consisted of one layer of ZrO2 beads covered by aluminum mesh electrodes; this porous structure of DFD part generates filter-type surface discharge and reactive oxygen species. In a closed cylindrical chamber, DFD treated air flow containing SARS-CoV-2 aerosols, primarily composed of particle diameters of ≤ 1 μm. A polypropylene melt-blown filter collected the treated bioaerosols for inactivation analysis. Plaque and polymerase chain reaction assays showed that the aerosolized SARS-CoV-2 that passed through the filter were more than 99.84% inactivated with degradation of SARS-CoV-2 genes (ORF1ab and E). However, ozone exposure without DFD passage was not found to be effective for bioaerosol inactivation in plaque assay.

SUBMITTER: Baek KH

PROVIDER: S-EPMC9119459 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Instant inactivation of aerosolized SARS-CoV-2 by dielectric filter discharge.

Baek Ki Ho KH Jang Donghwan D Kim Taeyoon T Park Joo Young JY Kim Dojoon D Ryoo Sungweon S Lee Seunghun S

PloS one 20220519 5

This study aimed to evaluate the instant inactivation effect of dielectric filter discharge (DFD) on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) aerosols. The filter consisted of one layer of ZrO2 beads covered by aluminum mesh electrodes; this porous structure of DFD part generates filter-type surface discharge and reactive oxygen species. In a closed cylindrical chamber, DFD treated air flow containing SARS-CoV-2 aerosols, primarily composed of particle diameters of ≤ 1 μm. A ...[more]

PMID: 35587941

Similar Datasets

Project description:COVID-19 is now a pandemic and the knowledge gap on SARS-CoV-2, i.e., the COVID-19 disease agent, dispersion persists. The US Centers for Disease Control and Prevention suggests fomites may not be the main route through which the novel coronavirus spreads. Supporting the same view, the latest the World Health Organization report recommends wearing masks for every individual in public, highlighting the transmission through the air. In the current study AERMOD, one of the most validated and tested models suggested by the USEPA, is used to model SARS-CoV-2-laden PM10 in a hypothetical outdoor environment. Multiple scenarios including particle size, wind speed, source height variations as well as and combined scenarios were modeled to estimated how exposure risk changes with the above-mentioned variables. The results reveal that wind speed majorly narrows infectious plume rather than transferring the peak concentration. The particle size variation indicated that small particles, i.e.,0.01 - 2.5 μm, could reach more than 9 m away from the source in concentration range of 10 - 20 (μg/m 3). On the other hand, source height contributes to peak plume shift rather than dispersing the infected particles. This idea was further studies by using combined scenarios which indicated height difference can impact peak plume displacement rather than wind speed. In the worst-case scenario, the results indicate that the virus-laden particles can travel outdoors more than 8 m away from an infected source. The video output of the model results clearly shows the dynamic of viral peak shifts in several scenarios. The results also indicate that in specific conditions the airborne SARS-CoV-2 can be transported to 9 m away from the source. These findings can be useful for individuals as well as decision-makers to mitigated exposure risk in real-world conditions.Supplementary informationThe online version contains supplementary material available at 10.1007/s40201-020-00602-9.

Dataset Information

Instant inactivation of aerosolized SARS-CoV-2 by dielectric filter discharge.

Publications

Instant inactivation of aerosolized SARS-CoV-2 by dielectric filter discharge.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets