Malaria transmission structure in the Peruvian Amazon through antibody signatures to Plasmodium vivax.

ABSTRACT:

Background

The landscape of malaria transmission in the Peruvian Amazon is temporally and spatially heterogeneous, presenting different micro-geographies with particular epidemiologies. Most cases are asymptomatic and escape routine malaria surveillance based on light microscopy (LM). Following the implementation of control programs in this region, new approaches to stratify transmission and direct efforts at an individual and community level are needed. Antibody responses to serological exposure markers (SEM) to Plasmodium vivax have proven diagnostic performance to identify people exposed in the previous 9 months.

Methodology

We measured antibody responses against 8 SEM to identify recently exposed people and determine the transmission dynamics of P. vivax in peri-urban (I

SUBMITTER: Rosado J 

PROVIDER: S-EPMC9119515 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature