The association of statin subgroups with lower urinary tract symptoms following a prostate biopsy.

ABSTRACT:

Introduction

This was a secondary analysis aiming to assess whether hydrophilic or hydrophobic statins have a differential effect on urinary retention (UR) and lower urinary tract symptoms (LUTS) in men following a prostate biopsy (PBx), who were at risk for prostate cancer development.

Methods

This was a population-based cohort study with data incorporated from the Institute for Clinical and Evaluative Sciences database to identify all Ontarian men aged 66 and above with a history of a single negative PBx between 1994 and 2016, with no drug prescription history of any of several putative chemo-preventative medications (statins, proton pump inhibitors, five-alpha-reductase inhibitors, and alpha-blockers). Multivariable Cox regression models with time-dependent covariates wer

SUBMITTER: Goldberg H 

PROVIDER: S-EPMC9119600 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature