Diurnal rhythm regulates the frequency of carbachol-induced beta oscillation via inhibitory neural system in rat hippocampus.

ABSTRACT: Animals have a diurnal rhythm with a cycle of approximately 1 day modulated by light information. This rhythm modulates memory performance. Relatedly, the hippocampal neural circuit has a dynamic property that can induce theta, beta, and gamma brain waves. However, the associated between the diurnal rhythm and these waves has not yet been elucidated. Carbachol, a cholinergic agent, can induce oscillations (e.g., beta waves) in rat hippocampal slices. In this study, we investigate the diurnal changes in the dynamic properties of hippocampal neuronal circuits using carbachol-induced beta oscillations (CIBOs). The hippocampal slices were made from rats adapted to 12-h-each light and dark conditions. The frequency of CIBO was significantly decreased more at midnight than at midday. There was n

SUBMITTER: Shigemoto M 

PROVIDER: S-EPMC9120310 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature