A Systematic Review and Meta-Analysis of Lipid Signatures in Post-traumatic Stress Disorder.

ABSTRACT:

Background

Research assessing lipid levels in individuals diagnosed with post-traumatic stress disorder (PTSD) has yielded mixed results. This study aimed to employ meta-analytic techniques to characterize the relationship between the levels of lipid profiles and PTSD.

Methods

We performed meta-analyses of studies comparing profiles and levels of lipids between PTSD patients and healthy individuals by searching Embase, Ovid Medline, Scopus, PsycINFO, and Cochrane databases for the studies until March 2021. Meta-analyses were performed using random-effects models with the restricted maximum-likelihood estimator to synthesize the effect size assessed by standardized mean difference (SMD) across studies.

Findings

A total of 8,657 abstracts were identified, and 17 studies

SUBMITTER: Bharti V 

PROVIDER: S-EPMC9120430 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature