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Laser coagulation and hemostasis of large diameter blood vessels: effect of shear stress and flow velocity.


ABSTRACT: Photocoagulation of blood vessels offers unambiguous advantages to current radiofrequency approaches considering the high specificity of blood absorption at available laser wavelengths (e.g., 532 nm and 1.064 µm). Successful treatment of pediatric vascular lesions, such as port-wine stains requiring microvascular hemostasis, has been documented. Although laser treatments have been successful in smaller diameter blood vessels, photocoagulation of larger sized vessels is less effective. The hypothesis for this study is that a primary limitation in laser coagulation of large diameter blood vessels (500-1000 µm) originates from shear stress gradients associated with higher flow velocities along with temperature-dependent viscosity changes. Laser (1.07 µm) coagulation of blood vessels was teste

SUBMITTER: Katta N 

PROVIDER: S-EPMC9120470 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature