Trajectory patterns of SARS-CoV-2 neutralising antibody response in convalescent COVID-19 patients.

ABSTRACT:

Background

The adaptive immune responses of COVID-19 patients contributes to virus clearance, restoration of health and protection from re-infection. The patterns of and the associated characteristics with longitudinal neutralising antibody (NAb) response following SARS-CoV-2 infection are important in their potential association with the population risks of re-infection.

Methods

This is a longitudinal study with blood samples and clinical data collected in adults aged 18 or above following diagnosis of SARS-CoV-2 infection. NAb levels were measured by the SARS-CoV-2 surrogate virus neutralisation test (sVNT). Anonymous clinical and laboratory data were matched with surveillance data for each subject for enabling analyses and applying latent class mixed models for trajectory

SUBMITTER: Wong NS 

PROVIDER: S-EPMC9120513 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature