Neuroprotection and neuroregeneration: roles for the white matter.

ABSTRACT: Efficient strategies for neuroprotection and repair are still an unmet medical need for neurodegenerative diseases and lesions of the central nervous system. Over the last few decades, a great deal of attention has been focused on white matter as a potential therapeutic target, mainly due to the discovery of the oligodendrocyte precursor cells in the adult central nervous system, a cell type able to fully repair myelin damage, and to the development of advanced imaging techniques to visualize and measure white matter lesions. The combination of these two events has greatly increased the body of research into white matter alterations in central nervous system lesions and neurodegenerative diseases and has identified the oligodendrocyte precursor cell as a putative target for white matter le

SUBMITTER: Baldassarro VA 

PROVIDER: S-EPMC9120696 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature