Presurgical cognitive status in patients with low-grade glioma and epilepsy: Testing the effects of seizures, antiseizure medications, and tumor localization.

ABSTRACT:

Background

Low-grade gliomas (LGGs) are frequently associated with epilepsy. There are few studies addressing the impact of seizures, antiseizure medications (ASMs), and lesion localization on presurgery cognitive functioning.

Methods

We tested the relation between the above-mentioned variables in a continuous series of 73 young patients (mean age 38.3 years ± 11.7) affected by LGGs and epilepsy. The anatomical areas, involved in this sample, were the left insula with surrounding cortical and subcortical areas, the right precentral gyrus/rolandic operculum, and the white matter and cortical regions beneath.

Results

Patients' presurgery cognitive status was within the normal range, with borderline performance for some tasks. We tested whether lower scores were related

SUBMITTER: Guarracino I 

PROVIDER: S-EPMC9120733 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature