Dataset Information

Quality of life predicts rehabilitation prognosis in Parkinson's disease patients: Factors influence rehabilitation prognosis: Factors influence rehabilitation prognosis.

ABSTRACT:

Background

Rehabilitation has been reported to improve the quality of life (QoL) of patients with Parkinson's disease (PD). Nevertheless, not all patients are satisfied with rehabilitation outcomes and could achieve a significant improvement in QoL.

Objective

To detect possible predictors of QoL improvement in patients with PD after rehabilitation.

Methods

A total of 86 PD patients were included and followed up for 3 months with a 39-item Parkinson's Disease Questionnaire summary index (PDQ-39 SI) as the primary endpoint. All patients received 2 weeks of multidisciplinary intensive rehabilitation treatment (MIRT). Changes in patients' QoL were assessed using the PDQ-39 at baseline and at the 3-month follow-up. The reliable change index (RCI) was adapted to determine the individual QoL outcome. The predictors of QoL outcome were detected using logistic regression analysis.

Results

After a 3-month follow-up, PDQ-39 SI decreased significantly from 22.95 ± 9.75 to 18.73 ± 10.32 (P < 0.001). Scores for QoL improved (RCI>10.9) after rehabilitation for 18.6% of the patients, and 74.4% of patients reported an unchanged QoL (-10.9≤RCI≤10.9), while 7.0% of patients reported a worsening of QoL (RCI<-10.9). Among the baseline parameters, the PDQ-39 SI was a baseline predictor for changes in QoL in the logistic regression model (OR: 1.15, CI: 1.07-1.24, P < 0.001).

Conclusions

MIRT could improve QoL for some patients with PD, and PDQ-39 score at baseline is the most important predictor for QoL improvements after rehabilitation for this patients.

SUBMITTER: Meng D

PROVIDER: S-EPMC9120870 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature

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Publications

Quality of life predicts rehabilitation prognosis in Parkinson's disease patients: Factors influence rehabilitation prognosis: Factors influence rehabilitation prognosis.

Meng Detao D Jin Zhaohui Z Chen Keke K Yu Xin X Wang Yixuan Y Du Wenjun W Wei Jingran J Xi Jianing J Fang Boyan B

Brain and behavior 20220416 5

<h4>Background</h4>Rehabilitation has been reported to improve the quality of life (QoL) of patients with Parkinson's disease (PD). Nevertheless, not all patients are satisfied with rehabilitation outcomes and could achieve a significant improvement in QoL.<h4>Objective</h4>To detect possible predictors of QoL improvement in patients with PD after rehabilitation.<h4>Methods</h4>A total of 86 PD patients were included and followed up for 3 months with a 39-item Parkinson's Disease Questionnaire s ...[more]

PMID: 35429406

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Dataset Information

Quality of life predicts rehabilitation prognosis in Parkinson's disease patients: Factors influence rehabilitation prognosis: Factors influence rehabilitation prognosis.

Background

Objective

Methods

Results

Conclusions

Publications

Quality of life predicts rehabilitation prognosis in Parkinson's disease patients: Factors influence rehabilitation prognosis: Factors influence rehabilitation prognosis.

Similar Datasets

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