Multidomain cognitive dysfunction after minor stroke suggests generalized disruption of cognitive networks.

ABSTRACT:

Objective

Although small strokes typically result in "good" functional outcomes, significant cognitive impairment can occur. This longitudinal study examined a cohort of patients with minor stroke to determine the pattern of deficits, evolution over time, and factors associated with outcome.

Methods

Patients admitted to the hospital with their first clinical minor stroke (NIH Stroke Scale [NIHSS] ≤ 10, absence of severe hemiparesis, aphasia, or neglect) were assessed at 1 month post-infarct, and a subset were followed over time (with 6- and 12-month evaluations). Composite scores at each time point were generated for global cognition, verbal memory, spatial memory, motor speed, processing speed, and executive function. Paired t-tests evaluated change in scores over time. Reg

SUBMITTER: Marsh EB 

PROVIDER: S-EPMC9120906 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature