Dog olfactory receptor gene expression profiling using samples derived from nasal epithelium brushing.

ABSTRACT: Dogs have an exquisite sense of olfaction. In many instances this ability has been utilized by humans for a wide range of important situations including detecting explosives and illegal drugs. It is accepted that some breeds have better senses of smell than others. Dogs can detect many volatile compounds at extremely low concentrations in air. To achieve such high levels of detection, the canine olfactory system is both complex and highly developed requiring a high density of olfactory receptors capable of detecting volatiles. Consequently the dog genome encodes a large number of olfactory receptor (OR) genes. However, it remains unclear as to what extent are all of these OR genes expressed on the cell surface. To facilitate such studies, a nasal brushing method was developed to recover do

SUBMITTER: Azzouzi N 

PROVIDER: S-EPMC9121576 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature