Ontology highlight
ABSTRACT:
SUBMITTER: James E
PROVIDER: S-EPMC9121913 | biostudies-literature | 2022 May
REPOSITORIES: biostudies-literature
James Eleanor E Ellis Cathy C Brassington Ruth R Sathasivam Sivakumar S Young Carolyn A CA
The Cochrane database of systematic reviews 20220520
<h4>Background</h4>Motor neuron disease (MND), also known as amyotrophic lateral sclerosis (ALS), is a progressive neurodegenerative condition that may cause dysphagia, as well as limb weakness, dysarthria, emotional lability, and respiratory failure. Since normal salivary production is 0.5 L to 1.5 L daily, loss of salivary clearance due to dysphagia leads to salivary pooling and sialorrhea, often resulting in distress and inconvenience to people with MND. This is an update of a review first pu ...[more]