Trends in the utilization of marginal donors for orthotopic heart transplantation.

ABSTRACT:

Background

This study explored trends in utilization of marginal donors for orthotopic heart transplantation (OHT) in the United States.

Methods

Using the United Network for Organ Sharing database, adults (≥18 years) undergoing OHT between 2009 and 2019 were identified. Marginal donors were defined as having ≥2 of the following: age ≥50 years, ejection fraction less than 50%, ischemic time greater than 240 min, donor-to-recipient body mass index ratio less than 0.8, or donor inotrope use. Kaplan-Meier analysis was utilized to model survival with multivariable Cox regression analysis used for risk-adjustment.

Results

A total of 23,580 recipients underwent OHT with 4896 (20.76%) receiving organs from marginal donors. The use of marginal donors decreased from 25.6% in 20

SUBMITTER: Huckaby LV 

PROVIDER: S-EPMC9122040 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature