Outcomes after primary and repeat thermal ablation of hepatocellular carcinoma with or without liver transplantation.

ABSTRACT:

Objectives

Thermal ablation (TA) is an established treatment for early HCC. There is a lack of data on the efficacy of repeated TA for recurrent HCC, resulting in uncertainty whether good oncologic outcomes can be obtained without performing orthotopic liver transplantation (OLTx). This study analyses outcomes after TA, with a special focus on repeat TA for recurrent HCC, either as a stand-alone therapy, or in relationship with OLTx.

Methods

Data from a prospectively registered database on interventions for HCC in a tertiary hepatobiliary centre was completed with follow-up until December 2020. Outcomes studied were rate of recurrence after primary TA and after its repeat interventions, the occurrence of untreatable recurrence, OS and DSS after primary and repeat TA, and com

SUBMITTER: Serbanescu-Kele Apor de Zalan CMC 

PROVIDER: S-EPMC9123025 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature