Singlet oxygen luminescence detector based on low-cost InGaAs avalanche photodiode.

ABSTRACT: Molecular oxygen excited to singlet state (Singlet oxygen, ¹O₂) becomes highly reactive and cytotoxic chemical. ¹O₂ is commonly generated by photoexcitation of dyes (photosensitizers), including the photodynamic therapy and diagnostics of cancer. However, the formation of singlet oxygen is often unwanted for various light-sensitive compounds, e.g. it causes the photobleaching of fluorescent probes. In either case, during a development of new photosensitive chemicals and drugs there is a need to evaluate the amount of ¹O₂ formed during photoexcitation. The direct approach in measuring the amount of singlet oxygen is based on the detection of its luminescence at 1270 nm. However, this luminescence is usually weak, which implie

SUBMITTER: Moskalensky AE 

PROVIDER: S-EPMC9123435 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature