Open-source hybrid 3D-bioprinter for simultaneous printing of thermoplastics and hydrogels.

ABSTRACT: 3D-bioprinting is a promising technology applicable in areas such as regenerative medicine or in vitro organ model development. Various 3D-bioprinting technologies and systems have been developed and are partly commercially available. Here, we present the construction and characterization of an open-source low-cost 3D-bioprinter that allows the alternated microextrusion of hydrogel and fused deposition modeling (FDM) of thermoplastic filaments. The presented 3D-bioprinter is based on a conventional Prusa i3 MK3 printer and features two independent printheads: the original FDM-head and a syringe-based microextrusion printhead for soft materials. Modifications were designed modularly to fit various syringe formats or heating elements to the device. The bioprinter is the first hybrid D

SUBMITTER: Koch F 

PROVIDER: S-EPMC9123455 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature