Incidence and Progression of Alcohol-Associated Liver Disease After Medical Therapy for Alcohol Use Disorder.

ABSTRACT:

Importance

Alcohol-associated liver disease (ALD) is one of the most devastating complications of alcohol use disorder (AUD), an increasingly prevalent condition. Medical addiction therapy for AUD may play a role in protecting against the development and progression of ALD.

Objective

To ascertain whether medical addiction therapy was associated with an altered risk of developing ALD in patients with AUD.

Design, setting, and participants

This retrospective cohort study used the Mass General Brigham Biobank, an ongoing research initiative that had recruited 127 480 patients between its start in 2010 and August 17, 2021, when data for the present study were retrieved. The mean follow-up duration from AUD diagnosis was 9.2 years. International Statistical Classification

SUBMITTER: Vannier AGL 

PROVIDER: S-EPMC9123494 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature