Early oral intake and early removal of nasogastric tube post-esophagectomy: A systematic review and meta-analysis.

ABSTRACT:

Background

Early oral intake (EOI: initiated within 1 day) and early nasogastric tube removal (ENR: removed ≤2 days) post-esophagectomy is controversial and subject to significant variation.

Aim

Our aim is to provide the most up-to-date evidence from published randomized controlled trials (RCTs) addressing both topics.

Methods

We searched MEDLINE and Embase (1946-06/2019) for RCTs that investigated the effect of EOI and/or ENR post-esophagectomy with gastric conduit for reconstruction. Our main outcomes of interest were anastomotic leak, aspiration pneumonia, mortality, and length of hospital stay (LOS). Pooled mean differences (MD) and risk ratios (RR) estimates were obtained using a DerSimonian random effects model.

Results

Two reviewers screened 613 abstract

SUBMITTER: Kaaki S 

PROVIDER: S-EPMC9124520 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature