Effects of Propofol on Hemodynamic Profile in Adults Receiving Targeted Temperature Management.

ABSTRACT: Background: Propofol is a key component for the management of sedation and shivering during targeted temperature management (TTM) following cardiac arrest. The cardiac depressant effects of propofol have not been described during TTM and may be especially relevant given the stress to the myocardium following cardiac arrest. The purpose of this study is to describe hemodynamic changes associated with propofol administration during TTM. Methods: This single center, retrospective cohort study evaluated adult patients who received a propofol infusion for at least 30 minutes during TTM. The primary outcome was the change in cardiovascular Sequential Organ Failure Assessment (cvSOFA) score 30 minutes after propofol initiation. Secondary outcomes included change in systolic blood pr

SUBMITTER: Hawkins WA 

PROVIDER: S-EPMC9125120 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature