Electroencephalography Signatures for Conditioned Pain Modulation and Pain Perception in Nonspecific Chronic Low Back Pain-An Exploratory Study.

ABSTRACT: Conditioned pain modulation (CPM) can discriminate between healthy and chronic pain patients. However, its relationship with neurophysiological pain mechanisms is poorly understood. Brain oscillations measured by electroencephalography (EEG) might help gain insight into this complex relationship.

Objective

To investigate the relationship between CPM response and self-reported pain intensity in non-specific chronic low back pain (NSCLBP) and explore respective EEG signatures associated to these mechanisms.

Design

Cross-sectional analysis.

Participants

Thirty NSCLBP patients participated.

Methods

Self-reported low back pain, questionnaires, mood scales, CPM (static and dynamic quantitative sensory tests), and resting surface EEG data were collected and analyzed. L

SUBMITTER: Teixeira PEP 

PROVIDER: S-EPMC9125498 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature