Exploring the risk factors and prognosis of transverse myelitis in systemic lupus erythematosus.

ABSTRACT:

Purpose

We aimed to describe the clinical characteristics and outcomes of patients with transverse myelitis (TM) as a rare manifestation in systemic lupus erythematosus (SLE) and explore the risk factors and prognosis of SLE-related TM (SLE-TM).

Methods

We conducted a retrospective case-control and cohort analysis. All patients with SLE-TM (58 patients) and 232 with SLE without TM, as a control group, were admitted to Peking Union Medical College Hospital between January 1993 and May 2021. Factors associated with the presence of SLE-TM and its prognosis were assessed using logistic regression and Cox proportional hazard models.

Results

Multivariate analysis revealed that positive anti-Ro/Sjogren's syndrome A (anti-Ro/ SSA) (<0.01) and increased erythrocyte sedimentati

SUBMITTER: Wang M 

PROVIDER: S-EPMC9125597 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature