Gut microbiota predicts body fat change following a low-energy diet: a PREVIEW intervention study.

ABSTRACT:

Background

Low-energy diets (LEDs) comprise commercially formulated food products that provide between 800 and 1200 kcal/day (3.3-5 MJ/day) to aid body weight loss. Recent small-scale studies suggest that LEDs are associated with marked changes in the gut microbiota that may modify the effect of the LED on host metabolism and weight loss. We investigated how the gut microbiota changed during 8 weeks of total meal replacement LED and determined their associations with host response in a sub-analysis of 211 overweight adults with pre-diabetes participating in the large multicentre PREVIEW (PREVention of diabetes through lifestyle intervention and population studies In Europe and around the World) clinical trial.

Methods

Microbial community composition was analysed by Illumina

SUBMITTER: Jian C 

PROVIDER: S-EPMC9125896 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature