Lack of association of post-discharge prophylactic antibiotics with decreased risk of surgical site infection following spinal fusion.

ABSTRACT:

Objectives

To determine the prevalence and factors associated with post-discharge prophylactic antibiotic use after spinal fusion and whether use was associated with decreased risk of surgical site infection (SSI).

Methods

Persons aged 10-64 years undergoing spinal fusion between 1 January 2010 and 30 June 2015 were identified in the MarketScan Commercial Database. Complicated patients and those coded for infection from 30 days before to 2 days after the surgical admission were excluded. Outpatient oral antibiotics were identified within 2 days of surgical discharge. SSI was defined using ICD-9-CM diagnosis codes within 90 days of surgery. Generalized linear models were used to determine factors associated with post-discharge prophylactic antibiotic use and with SSI.

Resu

SUBMITTER: Olsen MA 

PROVIDER: S-EPMC9126069 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature