Impact of measurement method on interobserver variability of apparent diffusion coefficient of lesions in prostate MRI

ABSTRACT:

Purpose

To compare the inter-observer variability of apparent diffusion coefficient (ADC) values of prostate lesions measured by 2D-region of interest (ROI) with and without specific measurement instruction.

Methods

Forty lesions in 40 patients who underwent prostate MR followed by targeted prostate biopsy were evaluated. A multi-reader study (10 readers) was performed to assess the agreement of ADC values between 2D-ROI without specific instruction and 2D-ROI with specific instruction to place a 9-pixel size 2D-ROI covering the lowest ADC area. The computer script generated multiple overlapping 9-pixel 2D-ROIs within a 3D-ROI encompassing the entire lesion placed by a single reader. The lowest mean ADC values from each 2D-small-ROI were used as reference values. Inter-ob

SUBMITTER: Takahashi H 

PROVIDER: S-EPMC9126398 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature