Variability in Test Interval Is Linked to Glycated Haemoglobin (HbA1c) Trajectory over Time.

ABSTRACT:

Aims

We previously showed that the glycated haemoglobin (HbA1c) testing frequency links to diabetes control. Here, we examine the effect of variability in test interval, adjusted for the frequency, on change in HbA1c (ΔHbA1c). Materials & Methods. HbA1c results were collected on 83,872 people with HbA1c results at baseline and 5 years (±3 months) later and ≥6 tests during this period. We calculated the standard deviation (SD) of test interval for each individual and examined the link between deciles of SD of the test interval and ΔHbA1c level, stratified by baseline HbA1c.

Results

In general, less variability in testing frequency (more consistent monitoring) was associated with better diabetes control. This was most evident with moderately raised baselin

SUBMITTER: Fryer AA 

PROVIDER: S-EPMC9126657 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature