Functional and Phenotypic Characterization of B Cells in the Teleost Adipose Tissue.

ABSTRACT: The immune response of the adipose tissue (AT) has been neglected in most animal models until investigations in human and mice linked obesity to chronic inflammation, highlighting the immune nature of this tissue. Despite this, in teleost fish, only a few studies have addressed the immune role of the AT. These studies have mostly focused on reporting transcriptional changes in the AT in response to diverse intraperitoneally delivered stimuli. Although the presence of B cells within the AT was also previously revealed, these cells have never been phenotypically or functionally characterized and this is what we have addressed in the current study. Initially, the B cell populations present in the rainbow trout (Oncorhynchus mykiss) AT were characterized in comparison to B cells from ot

SUBMITTER: Simon R 

PROVIDER: S-EPMC9127059 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature