Creatine Kinase and Mortality in Peritoneal Dialysis.

ABSTRACT:

Background

The association between serum creatine kinase and mortality in patients with peritoneal dialysis (PD) remained unknown.

Methods

We retrospectively collected data on 3,446 incident patients with from five PD centers in China between 1 January 2005 and 31 May 2020. Creatine kinase was collected 1 week before the start of PD. We examined the association between creatine kinase and mortality using Cox proportional hazards model.

Results

The median creatine kinase was 113 (range, 1.22-4,574) IU/L. With a median follow-up of 39.5 (range, 3.1-181.5) months, 763 (22.1%) all-cause deaths occurred, including 384 (11.1%) cardiovascular deaths. As compared with a creatine kinase of 111-179 IU/L (reference range), a higher creatine kinase (>179 IU/L) was associated with

SUBMITTER: Wu X 

PROVIDER: S-EPMC9127078 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature