SPIKES: Identification of physicochemical properties of spike proteins across diverse host species of SARS-CoV-2.

ABSTRACT: We describe a protocol to identify physicochemical properties using amino acid sequences of spike (S) proteins of SARS-CoV-2. We present an S protein prediction technique named SPIKES, incorporating an inheritable bi-objective combinatorial genetic algorithm to determine the host species specificity. This protocol addresses the S protein amino acid sequence data collection, preprocessing, methodology, and analysis. For complete details on the use and execution of this protocol, please refer to Yerukala Sathipati et al. (2022).

SUBMITTER: Yerukala Sathipati S 

PROVIDER: S-EPMC9127179 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature