Aortic Pulsatility Index: A New Haemodynamic Measure with Prognostic Value in Advanced Heart Failure.

ABSTRACT:

Aim

To test if the newly described haemodynamic variable, aortic pulsatility index (API), predicts long-term prognosis in advanced heart failure (HF).

Methods

A single-centre study on 453 HF patients (median age: 51 years; left ventricular ejection fraction [LVEF]: 19% ± 9%) referred for right heart catheterisation. API was calculated as pulse pressure/pulmonary capillary wedge pressure.

Results

Log(API) correlated significantly with central venous pressure (CVP; p<0.001) and cardiac index (p<0.001) in univariable regression analysis. CVP remained associated with log(API) in a multivariable analysis including cardiac index, heart rate, log(NT-proBNP [N-terminal proB-type natriuretic peptide]), LVEF, New York Heart Association (NYHA) class III or IV and sex (p=0.01). I

SUBMITTER: Deis T 

PROVIDER: S-EPMC9127634 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature