Flow-controlled ventilation in moderate acute respiratory distress syndrome due to COVID-19: an open-label repeated-measures controlled trial.

ABSTRACT:

Background

Flow-controlled ventilation (FCV), a novel mode of mechanical ventilation characterised by constant flow during active expiration, may result in more efficient alveolar gas exchange, better lung recruitment and might be useful in limiting ventilator-induced lung injury. However, data regarding FCV in mechanically ventilated patients with acute lung injury or acute respiratory distress syndrome (ARDS) are scarce.

Objectives

We hypothesised that the use of FCV is feasible and would improve oxygenation in moderate COVID-19 ARDS compared to conventional ventilation.

Design

Open-label repeated-measures controlled trial.

Setting

From February to April 2021, patients with moderate COVID-19 ARDS were recruited in a tertiary referral intensive care unit.

P

SUBMITTER: Van Dessel ED 

PROVIDER: S-EPMC9127816 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature