Individuals with Higher Levels of Physical Activity after Stroke Show Comparable Patterns of Myelin to Healthy Older Adults.

ABSTRACT:

Background

Myelin asymmetry ratios (MARs) relate and contribute to motor impairment and function after stroke. Physical activity (PA) may induce myelin plasticity, potentially mitigating hemispheric myelin asymmetries that can occur after a stroke.

Objective

The aim of this study was to determine whether individuals with higher levels of PA showed lower MAR compared to individuals with lower levels of PA.

Methods

Myelin water fraction was obtained from 5 bilateral motor regions in 22 individuals with chronic stroke and 26 healthy older adults. Activity levels were quantified with wrist accelerometers worn for a period of 72 hours (3 days). Higher and lower PA levels were defined by a cluster analysis within each group.

Results

MAR was similar regardless of PA l

SUBMITTER: Greeley B 

PROVIDER: S-EPMC9127936 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature