Association Between Dietary Inflammatory Index and S-Klotho Plasma Levels in Middle-Aged and Elderly People.

ABSTRACT:

Background and aims

Soluble Klotho (S-Klotho) is a protein that has anti-aging properties. Dietary inflammation index (DII) is closely related to various age-related diseases. However, whether DII is related to S-Klotho plasma levels is still controversial. It was the goal of this study to examine the link between DII and S-Klotho in middle-aged and elderly people.

Methods

Between 2007 and 2016, five NHANES cycles were conducted, with 12,315 middle-aged and elderly (aged 40-79) participants having S-Klotho tests and submitting dietary recall data. The inflammatory potential of a diet was determined using the DII. To determine the plasma levels of S-Klotho, we employed a solid-phase sandwich enzyme-linked immunosorbent assay (ELISA).

Results

There was a negative correl

SUBMITTER: Ma TC 

PROVIDER: S-EPMC9127966 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature