Molecular Evaluation of Human Parvovirus B19 Infection and Associated Risk Factors among Pregnant Women in Bushehr Province, Southern Iran.

ABSTRACT: Given the importance of human parvovirus B19 infection during pregnancy and the potential risks to the fetus, this study was designed to determine the prevalence, genotypic pattern, and risk factors of parvovirus B19 infection among a population-based sample of pregnant women in Bushehr Province, southern Iran. A total of 824 pregnant women were enrolled in this study. Serum samples were screened for the detection of anti-parvovirus B19 IgM and IgG by ELISA. The molecular evaluation was performed by nested polymerase chain reaction, targeting the non-structural protein 1-viral protein 1 unique region of the genome, and sequencing. Of 824 pregnant women, 330 (40.1%) were positive for anti-parvovirus B19 IgG and 50 women (6.1%) had anti-parvovirus B19 IgM. A greater rate of anti-parvovirus B

SUBMITTER: Taherkhani R 

PROVIDER: S-EPMC9128684 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature