Vaginal ring acceptability: A systematic review and meta-analysis of vaginal ring experiences from around the world.

ABSTRACT:

Objective

The vaginal ring (ring) is a female-initiated, long-acting drug delivery system for different indications, including HIV prevention. Our aim was to provide evidence for acceptability of the vaginal ring across indications to support dapivirine and multipurpose prevention technology ring introduction and roll out.

Study design

This systematic review and meta-analysis followed PRISMA guidelines. We searched PubMed, Web of Science, Embase, and grey literature for publications reporting favorable ring acceptability and secondary outcomes involving actual ring use (comfort, ease of ring use, ring comfort during sex, expulsions, and vaginal symptoms) or hypothetical acceptability for any indication published January 1, 1970-June 15, 2021. We estimated random-effects pool

SUBMITTER: Ridgeway K 

PROVIDER: S-EPMC9128798 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature