A Longitudinal Study of COVID-19 Sequelae and Immunity: Baseline Findings.

ABSTRACT:

Background

A substantial proportion of persons who develop COVID-19 report persistent symptoms after acute illness. Various pathophysiologic mechanisms have been implicated in the pathogenesis of postacute sequelae of SARS-CoV-2 infection (PASC).

Objective

To characterize medical sequelae and persistent symptoms after recovery from COVID-19 in a cohort of disease survivors and controls.

Design

Cohort study. (ClinicalTrials.gov: NCT04411147).

Setting

National Institutes of Health Clinical Center, Bethesda, Maryland.

Participants

Self-referred adults with laboratory-documented SARS-CoV-2 infection who were at least 6 weeks from symptom onset were enrolled regardless of presence of PASC. A control group comprised persons with no history of COVID-19 or serol

SUBMITTER: Sneller MC 

PROVIDER: S-EPMC9128805 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature