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Brain natriuretic peptide measurements using standard biochemical equipment: Comparisons with conventional immunoassays.


ABSTRACT:

Background

Brain natriuretic peptide (BNP) is an essential cardiac biomarker for diagnosing heart failure and for prognoses in patients with various cardiac diseases. However, measurement requires immunological assays that are not available in every hospital. Recently, a novel BNP kit (Nanopia BNP-A, Sekisui Inc.; BNPn) that uses general-purpose, automated, biochemical analyzers has become commercially available. We assessed how its accuracy and utility compare with those of conventional immunological tests.

Methods and results

We retrospectively collected 1491 conventional BNP measurements (BNPc), which had been clinically indicated for BNP testing and for which residual samples were still stored in the laboratory. We measured BNP using the novel kit and determined the corr

SUBMITTER: Higa Y 

PROVIDER: S-EPMC9128988 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature