Antibody response with SARS-CoV-2 inactivated vaccine (CoronaVac) in Turkish geriatric population.

ABSTRACT:

Background

Sars-CoV-2 infection influences older individuals at the forefront, and there is still limited data on the COVID-19 vaccine response in the geriatric population. This study aimed to assess antibody response after vaccination with SARS-CoV-2 inactivated vaccine and examine possible factors affecting this response in a geriatric population.

Methods

individuals who have been on at least the 28th day after the second dose of the COVID-19 vaccine were included. Comprehensive geriatric assessment tools and the Clinical Frailty Scale were performed. SARS-CoV-2 spike-specific IgG antibodies were detected and, levels ≥1 U/ml were defined as seropositive, <1 U/ml were defined as seronegative.

Results

a total of 497 patients were included and divided into three groups

SUBMITTER: Okyar Bas A 

PROVIDER: S-EPMC9129137 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature