Vasectomy and Risk of Prostate Cancer: A Systematic Review and Meta-analysis.

ABSTRACT:

Context

Previous reports have shown an association between vasectomy and prostate cancer (PCa). However, there exist significant discrepancies between studies and systematic reviews due to a lack of strong causal association and residual confounding factors such as prostate-specific antigen (PSA) screening.

Objective

To assess the association between vasectomy and PCa, in both unadjusted and PSA screen-adjusted studies.

Evidence acquisition

We performed a systematic review according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses. The PubMed, Scopus, and Web of Science databases were searched in January 2022 for studies that analyzed the association between vasectomy and PCa.

Evidence synthesis

A total of 37 studies including 16 931 80

SUBMITTER: Baboudjian M 

PROVIDER: S-EPMC9130083 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature